The Potential Side Effects of TRT

TRT Is Powerful—but It’s Not Without Risks
Testosterone Replacement Therapy (TRT) can offer incredible benefits when done right. But like any medical treatment, it’s important to understand the potential risks and side effects before starting. At Testosteronerehab, our goal is to help you achieve hormonal balance safely, effectively, and with full transparency. Here’s what you need to know.
ADAM Questionnaire Low Testosterone Test
The ADAM questionnaire is 88% sensitive in detecting low testosterone.
Hormonal Suppression & Fertility Issues
When your body detects external testosterone, it may slow or stop its natural production. This can lead to reduced sperm production, testicular shrinkage, and temporary infertility. Thankfully, we address this using treatments like HCG or HMG to keep your fertility protected while on TRT.

Acne & Oily Skin
Increased testosterone levels can cause the skin to produce more oil, which may lead to mild to moderate acne, especially in the early stages of treatment. This side effect is usually temporary and can be managed through proper dosing and skincare.
Blood Test Testosterone test kits
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Increased Red Blood Cell Count
TRT may stimulate the production of red blood cells, which in some cases can thicken the blood—raising the risk of high blood pressure or blood clots. Regular blood tests help us track these levels and make any necessary adjustments to keep you safe.
Fluid Retention & Swelling
Some men experience mild water retention, especially at the beginning of treatment. This can cause puffiness or slight weight gain, typically in the ankles or hands. It’s often a temporary adjustment that stabilizes over time.
Blood Test Testosterone test kits
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Mood Changes or Irritability
While TRT often improves mood and mental clarity, imbalanced hormone levels (especially with poor management) may lead to irritability or mood swings in some cases. This is why we emphasize regular monitoring and personalised dosing at Testosteronerehab.
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Contact us for more information on low testosterone or TRT.
Sleep Apnea Exacerbation
Men with undiagnosed or existing sleep apnea may experience worsening symptoms on TRT. This is something we actively screen for in our assessments, ensuring your therapy supports—not disrupts—your rest and recovery.
The Importance of Medical Supervision
Many of the risks associated with TRT arise when therapy is poorly managed, unmonitored, or self-administered. At Testosteronerehab, we ensure every step of your journey—from blood work to dosing—is carefully overseen by experienced professionals who prioritise your health and safety.
Our Commitment to Safe, Effective TRT
We don’t believe in shortcuts or guesswork. Our team designs custom treatment plans, performs routine testing, and supports you with expert care every step of the way. By staying informed and monitored, you can enjoy the life-changing benefits of TRT while minimizing risks.
Know the Risks, Own the Results
When done right, TRT can be life-changing. But knowing the potential side effects—and how to prevent or manage them—is key to a successful journey. With the right team and the right strategy, you don’t just balance hormones—you take back control of your health, confidence, and future.
Contact Us For more information
Contact us for more information on low testosterone or TRT.